abstract：BACKGROUND:Cardiovascular disease (CVD) is the leading cause of death in the United States. PURPOSE:To update a systematic review about the benefits of aspirin for the primary prevention of cardiovascular events in adults aged 40 years or older and to evaluate effect modification in subpopulations. DATA SOURCES:MEDLI...

journal_title：Annals of internal medicine

authors： Guirguis-Blake JM,Evans CV,Senger CA,O'Connor EA,Whitlock EP

更新日期：2016-06-21 00:00:00

abstract：BACKGROUND:Recent postmarketing trials produced conflicting results about the risk for hospitalized heart failure (hHF) associated with dipeptidyl peptidase-4 (DPP-4) inhibitors, creating uncertainty about the safety of these antihyperglycemic agents. OBJECTIVE:To examine the associations of hHF with saxagliptin and s...

journal_title：Annals of internal medicine

authors： Toh S,Hampp C,Reichman ME,Graham DJ,Balakrishnan S,Pucino F,Hamilton J,Lendle S,Iyer A,Rucker M,Pimentel M,Nathwani N,Griffin MR,Brown NJ,Fireman BH

更新日期：2016-06-07 00:00:00

abstract：BACKGROUND:The effect of physician diagnostic variability on accuracy at a population level depends on the prevalence of diagnoses. OBJECTIVE:To estimate how diagnostic variability affects accuracy from the perspective of a U.S. woman aged 50 to 59 years having a breast biopsy. DESIGN:Applied probability using Bayes'...

journal_title：Annals of internal medicine

authors： Elmore JG,Nelson HD,Pepe MS,Longton GM,Tosteson AN,Geller B,Onega T,Carney PA,Jackson SL,Allison KH,Weaver DL

更新日期：2016-05-17 00:00:00

abstract：:Bioethics has become a common course of study in medical schools, other health professional schools, and graduate and undergraduate programs. An analysis of past ethical scandals, as well as the bioethics apparatus that emerged in response to them, is often central to the discussion of bioethical questions. This histo...

journal_title：Annals of internal medicine

authors： Lerner BH,Caplan AL

更新日期：2016-04-19 00:00:00

abstract：BACKGROUND:Recent evidence shows that arthroscopic partial meniscectomy (APM) offers no benefit over conservative treatment of patients with a degenerative meniscus tear. However, patients who report mechanical symptoms (sensations of knee catching or locking) may benefit from APM. OBJECTIVE:To assess whether APM impr...

journal_title：Annals of internal medicine

authors： Sihvonen R,Englund M,Turkiewicz A,Järvinen TL,Finnish Degenerative Meniscal Lesion Study Group.

更新日期：2016-04-05 00:00:00

abstract：BACKGROUND:The fecal immunochemical test (FIT) is a common method for colorectal cancer (CRC) screening, yet its acceptability and performance over several rounds of annual testing are largely unknown. OBJECTIVE:To assess FIT performance characteristics over 4 rounds of annual screening. DESIGN:Retrospective cohort s...

journal_title：Annals of internal medicine

authors： Jensen CD,Corley DA,Quinn VP,Doubeni CA,Zauber AG,Lee JK,Zhao WK,Marks AR,Schottinger JE,Ghai NR,Lee AT,Contreras R,Klabunde CN,Quesenberry CP,Levin TR,Mysliwiec PA

更新日期：2016-04-05 00:00:00

abstract：BACKGROUND:Two recent double-blind, randomized, controlled trials (RCTs) showed that oral steroids and nonsteroidal anti-inflammatory drugs have similar analgesic effectiveness for management of gout, but the trials had small sample sizes and other methodological limitations. OBJECTIVE:To compare the effectiveness and...

journal_title：Annals of internal medicine

authors： Rainer TH,Cheng CH,Janssens HJ,Man CY,Tam LS,Choi YF,Yau WH,Lee KH,Graham CA

更新日期：2016-04-05 00:00:00

abstract：BACKGROUND:Estimates of risk for radiation-induced breast cancer from mammography screening have not considered variation in dose exposure or diagnostic work-up after abnormal screening results. OBJECTIVE:To estimate distributions of radiation-induced breast cancer incidence and mortality from digital mammography scre...

journal_title：Annals of internal medicine

authors： Miglioretti DL,Lange J,van den Broek JJ,Lee CI,van Ravesteyn NT,Ritley D,Kerlikowske K,Fenton JJ,Melnikow J,de Koning HJ,Hubbard RA

更新日期：2016-02-16 00:00:00

abstract：DESCRIPTION:Update of the 2009 U.S. Preventive Services Task Force (USPSTF) recommendation on screening for breast cancer. METHODS:The USPSTF reviewed the evidence on the following: effectiveness of breast cancer screening in reducing breast cancer-specific and all-cause mortality, as well as the incidence of advanced...

journal_title：Annals of internal medicine

authors： Siu AL,U.S. Preventive Services Task Force.

更新日期：2016-02-16 00:00:00

abstract：:Behavioral economics provides insights about the development of effective incentives for physicians to deliver high-value care. It suggests that the structure and delivery of incentives can shape behavior, as can thoughtful design of the decision-making environment. This article discusses several principles of behavio...

journal_title：Annals of internal medicine

authors： Emanuel EJ,Ubel PA,Kessler JB,Meyer G,Muller RW,Navathe AS,Patel P,Pearl R,Rosenthal MB,Sacks L,Sen AP,Sherman P,Volpp KG

更新日期：2016-01-19 00:00:00

abstract：BACKGROUND:Treatment of chronic hepatitis C virus (HCV) infection with direct-acting antivirals (DAAs) for 6 weeks achieves sustained virologic response (SVR) rates of 95% in some patients. If effective, shorter therapeutic courses could improve adherence and treatment costs. OBJECTIVE:To determine factors predictive ...

journal_title：Annals of internal medicine

authors： Kohli A,Kattakuzhy S,Sidharthan S,Nelson A,McLaughlin M,Seamon C,Wilson E,Meissner EG,Sims Z,Silk R,Gross C,Akoth E,Tang L,Price A,Jolley TA,Emmanuel B,Proschan M,Teferi G,Chavez J,Abbott S,Osinusi A,Mo H,Poli

更新日期：2015-12-15 00:00:00

abstract：BACKGROUND:Whether behavioral approaches for self-management programs benefit individuals with type 1 diabetes mellitus is unclear. PURPOSE:To determine the effects of behavioral programs for patients with type 1 diabetes on behavioral, clinical, and health outcomes and to investigate factors that might moderate effec...

journal_title：Annals of internal medicine

authors： Pillay J,Armstrong MJ,Butalia S,Donovan LE,Sigal RJ,Chordiya P,Dhakal S,Vandermeer B,Hartling L,Nuspl M,Featherstone R,Dryden DM

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Leukotriene-receptor antagonists (LTRAs) are recommended as an alternative treatment in patients with mild asthma, but their effect compared with placebo is unclear. PURPOSE:To determine the benefits and harms of LTRAs as monotherapy or in combination with inhaled corticosteroids compared with placebo in ad...

journal_title：Annals of internal medicine

authors： Miligkos M,Bannuru RR,Alkofide H,Kher SR,Schmid CH,Balk EM

更新日期：2015-11-17 00:00:00

abstract：BACKGROUND:Common diseases, particularly dementia, have large social costs for the U.S. population. However, less is known about the end-of-life costs of specific diseases and the associated financial risk for individual households. OBJECTIVE:To examine social costs and financial risks faced by Medicare beneficiaries ...

journal_title：Annals of internal medicine

authors： Kelley AS,McGarry K,Gorges R,Skinner JS

更新日期：2015-11-17 00:00:00

abstract：BACKGROUND:Tobacco use is the leading cause of preventable death in the United States. PURPOSE:To review the effectiveness and safety of pharmacotherapy and behavioral interventions for tobacco cessation. DATA SOURCES:5 databases and 8 organizational Web sites were searched through 1 August 2014 for systematic review...

journal_title：Annals of internal medicine

authors： Patnode CD,Henderson JT,Thompson JH,Senger CA,Fortmann SP,Whitlock EP

更新日期：2015-10-20 00:00:00

abstract：DESCRIPTION:Update of the 2009 U.S. Preventive Services Task Force (USPSTF) recommendation on counseling and interventions to prevent tobacco use and tobacco-related disease in adults, including pregnant women. METHODS:The USPSTF reviewed the evidence on interventions for tobacco smoking cessation that are relevant to...

journal_title：Annals of internal medicine

authors： Siu AL,U.S. Preventive Services Task Force.

更新日期：2015-10-20 00:00:00

abstract：BACKGROUND:Medicare's value-based purchasing (VBP) and the Hospital Readmissions Reduction Program (HRRP) could disproportionately affect safety-net hospitals. OBJECTIVE:To determine whether safety-net hospitals incur larger financial penalties than other hospitals under VBP and HRRP. DESIGN:Cross-sectional analysis....

journal_title：Annals of internal medicine

authors： Gilman M,Hockenberry JM,Adams EK,Milstein AS,Wilson IB,Becker ER

更新日期：2015-09-15 00:00:00

abstract：BACKGROUND:Impressive decreases in cardiovascular mortality have been achieved through risk factor reduction and clinical intervention, yet cardiovascular disease remains a leading cause of death nationally. OBJECTIVE:To estimate up-to-date preventable fractions of cardiovascular mortality associated with elimination ...

journal_title：Annals of internal medicine

authors： Patel SA,Winkel M,Ali MK,Narayan KM,Mehta NK

更新日期：2015-08-18 00:00:00

abstract：BACKGROUND:Motor vehicle crashes (MVCs) remain a leading cause of injury-related deaths in the United States. Primary seat belt laws allow vehicle occupants to be ticketed solely for not wearing seat belts, and secondary laws allow ticketing only for failure to wear seat belts in the setting of other violations. OBJEC...

journal_title：Annals of internal medicine

authors： Lee LK,Monuteaux MC,Burghardt LC,Fleegler EW,Nigrovic LE,Meehan WP,Schutzman SA,Mannix R

更新日期：2015-08-04 00:00:00

abstract：BACKGROUND:Because psychological approaches are likely to produce sustained benefits without the risk for tolerance or adverse effects associated with pharmacologic approaches, cognitive behavioral therapy for insomnia (CBT-i) is now commonly recommended as first-line treatment for chronic insomnia. PURPOSE:To determi...

journal_title：Annals of internal medicine

authors： Trauer JM,Qian MY,Doyle JS,Rajaratnam SM,Cunnington D

更新日期：2015-08-04 00:00:00

abstract：BACKGROUND:Initiation of antiretroviral therapy (ART) during tuberculosis (TB) treatment remains challenging. PURPOSE:To assess evidence from randomized, controlled trials of the timing of ART initiation in HIV-infected adults with newly diagnosed pulmonary TB. DATA SOURCES:PubMed, EMBASE, Cochrane Central Register o...

journal_title：Annals of internal medicine

authors： Uthman OA,Okwundu C,Gbenga K,Volmink J,Dowdy D,Zumla A,Nachega JB

更新日期：2015-07-07 00:00:00

abstract：BACKGROUND:A daily injection of low-molecular-weight heparin (LMWH) is often prescribed to women with unexplained recurrent pregnancy loss (RPL), although evidence suggesting a benefit is questionable. OBJECTIVE:To determine whether LMWH increases ongoing pregnancy and live-birth rates in women with unexplained RPL. ...

journal_title：Annals of internal medicine

authors： Schleussner E,Kamin G,Seliger G,Rogenhofer N,Ebner S,Toth B,Schenk M,Henes M,Bohlmann MK,Fischer T,Brosteanu O,Bauersachs R,Petroff D,ETHIG II group.

更新日期：2015-05-05 00:00:00

abstract：:Deaths and injuries related to firearms constitute a major public health problem in the United States. In response to firearm violence and other firearm-related injuries and deaths, an interdisciplinary, interprofessional group of leaders of 8 national health professional organizations and the American Bar Association...

journal_title：Annals of internal medicine

authors： Weinberger SE,Hoyt DB,Lawrence HC 3rd,Levin S,Henley DE,Alden ER,Wilkerson D,Benjamin GC,Hubbard WC

更新日期：2015-04-07 00:00:00

abstract：:This article applies major economic concepts, such as supply, demand, monopoly, monopsony, adverse selection, and moral hazard, to central features of U.S. health care. These illustrations help explain some of the principal problems of health policy-high cost and the uninsured-and why solutions are difficult to obtain...

journal_title：Annals of internal medicine

authors： Fuchs VR

更新日期：2015-03-03 00:00:00

abstract：BACKGROUND:Elevated blood pressure (BP) is the largest contributing risk factor to all-cause and cardiovascular mortality. PURPOSE:To update a systematic review on the benefits and harms of screening for high BP in adults and to summarize evidence on rescreening intervals and diagnostic and predictive accuracy of diff...

journal_title：Annals of internal medicine

authors： Piper MA,Evans CV,Burda BU,Margolis KL,O'Connor E,Whitlock EP

更新日期：2015-02-03 00:00:00

abstract：BACKGROUND:Many states have laws requiring mammography facilities to tell women with dense breasts and negative results on screening mammography to discuss supplemental screening tests with their providers. The most readily available supplemental screening method is ultrasonography, but little is known about its effect...

journal_title：Annals of internal medicine

authors： Sprague BL,Stout NK,Schechter C,van Ravesteyn NT,Cevik M,Alagoz O,Lee CI,van den Broek JJ,Miglioretti DL,Mandelblatt JS,de Koning HJ,Kerlikowske K,Lehman CD,Tosteson AN

更新日期：2015-02-03 00:00:00

abstract：BACKGROUND:The magnitude, consistency, and manner of association between sedentary time and outcomes independent of physical activity remain unclear. PURPOSE:To quantify the association between sedentary time and hospitalizations, all-cause mortality, cardiovascular disease, diabetes, and cancer in adults independent ...

journal_title：Annals of internal medicine

authors： Biswas A,Oh PI,Faulkner GE,Bajaj RR,Silver MA,Mitchell MS,Alter DA

更新日期：2015-01-20 00:00:00

abstract：:The TRIPOD (Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis) Statement includes a 22-item checklist, which aims to improve the reporting of studies developing, validating, or updating a prediction model, whether for diagnostic or prognostic purposes. The TRIPOD Statement...

journal_title：Annals of internal medicine

authors： Moons KG,Altman DG,Reitsma JB,Ioannidis JP,Macaskill P,Steyerberg EW,Vickers AJ,Ransohoff DF,Collins GS

更新日期：2015-01-06 00:00:00

abstract：BACKGROUND:Previous research has supported screening for gonorrhea and chlamydia in asymptomatic, sexually active women (including pregnant women) who are younger than 25 years or at increased risk but not in other patient populations. PURPOSE:To update the 2005 and 2007 systematic reviews for the U.S. Preventive Serv...

journal_title：Annals of internal medicine

authors： Zakher B,Cantor AG,Pappas M,Daeges M,Nelson HD

更新日期：2014-12-16 00:00:00

abstract：BACKGROUND:Depression collaborative care implementation using community engagement and planning (CEP) across programs improves 6-month client outcomes in minority communities, compared with technical assistance to individual programs (resources for services [RS]). However, 12-month outcomes are unknown. OBJECTIVE:To c...

journal_title：Annals of internal medicine

authors： Chung B,Ong M,Ettner SL,Jones F,Gilmore J,McCreary M,Sherbourne C,Ngo V,Koegel P,Tang L,Dixon E,Miranda J,Belin TR,Wells KB

更新日期：2014-11-18 00:00:00

abstract：BACKGROUND:Hospitals are implementing discharge support programs to reduce readmissions, and these programs have had mixed success. OBJECTIVE:To examine whether a peridischarge, nurse-led intervention decreased emergency department (ED) visits or readmissions among ethnically and linguistically diverse older patients ...

journal_title：Annals of internal medicine

authors： Goldman LE,Sarkar U,Kessell E,Guzman D,Schneidermann M,Pierluissi E,Walter B,Vittinghoff E,Critchfield J,Kushel M

更新日期：2014-10-07 00:00:00

abstract：BACKGROUND:Several adverse outcomes attributed to atypical antipsychotic drugs, specifically quetiapine, risperidone, and olanzapine, are known to cause acute kidney injury (AKI). Such outcomes include hypotension, acute urinary retention, and the neuroleptic malignant syndrome or rhabdomyolysis. OBJECTIVE:To investig...

journal_title：Annals of internal medicine

authors： Hwang YJ,Dixon SN,Reiss JP,Wald R,Parikh CR,Gandhi S,Shariff SZ,Pannu N,Nash DM,Rehman F,Garg AX

更新日期：2014-08-19 00:00:00

abstract：DESCRIPTION:Update of the 2005 U.S. Preventive Services Task Force (USPSTF) recommendation on screening for abdominal aortic aneurysm (AAA). METHODS:The USPSTF commissioned a systematic review that assessed the evidence on the benefits and harms of screening for AAA and strategies for managing small (3.0 to 5.4 cm) sc...

journal_title：Annals of internal medicine

authors： LeFevre ML,U.S. Preventive Services Task Force.

更新日期：2014-08-19 00:00:00

abstract：BACKGROUND:Corticosteroid injections (CSIs) and physical therapy are used to treat patients with the shoulder impingement syndrome (SIS) but have never been directly compared. OBJECTIVE:To compare the effectiveness of 2 common nonsurgical treatments for SIS. DESIGN:Randomized, single-blind, comparative-effectiveness,...

journal_title：Annals of internal medicine

authors： Rhon DI,Boyles RB,Cleland JA

更新日期：2014-08-05 00:00:00

abstract：BACKGROUND:Changes in federal health policy are providing more access to medical care for persons with chronic disease. Providing quality care may require a team approach, which the American College of Physicians calls the "medical home." One new model may involve nurse-managed protocols. PURPOSE:To determine whether ...

journal_title：Annals of internal medicine

authors： Shaw RJ,McDuffie JR,Hendrix CC,Edie A,Lindsey-Davis L,Nagi A,Kosinski AS,Williams JW Jr

更新日期：2014-07-15 00:00:00

abstract：BACKGROUND:Nearly 25% of patients hospitalized with heart failure (HF) are readmitted within 30 days. PURPOSE:To assess the efficacy, comparative effectiveness, and harms of transitional care interventions to reduce readmission and mortality rates for adults hospitalized with HF. DATA SOURCES:MEDLINE, Cochrane Librar...

journal_title：Annals of internal medicine

authors： Feltner C,Jones CD,Cené CW,Zheng ZJ,Sueta CA,Coker-Schwimmer EJ,Arvanitis M,Lohr KN,Middleton JC,Jonas DE

更新日期：2014-06-03 00:00:00

abstract：BACKGROUND:Preeclampsia is a leading cause of maternal and perinatal morbidity and mortality. PURPOSE:To systematically review benefits and harms of low-dose aspirin for preventing morbidity and mortality from preeclampsia. DATA SOURCES:MEDLINE, Database of Abstracts of Reviews of Effects, PubMed, and Cochrane Centra...

journal_title：Annals of internal medicine

authors： Henderson JT,Whitlock EP,O'Connor E,Senger CA,Thompson JH,Rowland MG

更新日期：2014-05-20 00:00:00

abstract：BACKGROUND:ClinicalTrials.gov requires reporting of result summaries for many drug and device trials. PURPOSE:To evaluate the consistency of reporting of trials that are registered in the ClinicalTrials.gov results database and published in the literature. DATA SOURCES:ClinicalTrials.gov results database and matched ...

journal_title：Annals of internal medicine

authors： Hartung DM,Zarin DA,Guise JM,McDonagh M,Paynter R,Helfand M

更新日期：2014-04-01 00:00:00

abstract：:The U.S. Preventive Services Task Force (USPSTF) makes recommendations on which preventive services to routinely incorporate into primary care for specific populations. Behavioral counseling interventions are preventive services designed to help persons engage in healthy behaviors and limit unhealthy ones. The USPSTF'...

journal_title：Annals of internal medicine

authors： Curry SJ,Grossman DC,Whitlock EP,Cantu A

更新日期：2014-03-18 00:00:00

abstract：BACKGROUND:The choice of antiplatelet therapy after acute coronary syndrome (ACS) is complicated: Ticagrelor and prasugrel are novel alternatives to clopidogrel, patients with some genotypes may not respond to clopidogrel, and low-cost generic formulations of clopidogrel are available. OBJECTIVE:To determine the most ...

journal_title：Annals of internal medicine

authors： Kazi DS,Garber AM,Shah RU,Dudley RA,Mell MW,Rhee C,Moshkevich S,Boothroyd DB,Owens DK,Hlatky MA

更新日期：2014-02-18 00:00:00